Conservative treatment is the main therapy for cervicobrachial syndrome, scapulohumeral periarthritis, and lumbago as diseases with both pain and muotonia. The conservative treatmnet mainly consists of medication, physiotherapy, and
kinesiotherapy.
In
the recent years, attemptos have been made to give relief to myotonia through combination therapy with antiinflammatory analgesics and muscle relaxants. The muscle relaxants using in general are tolperisone hydrochlorinde, chlormezanone, and
diazepam.
Eperizone hydrochloride(Mulex tablet) is a β-propriophenone derivatives and a central acting muscle relaxant, And it benefited subjective symptoms such as muscular pain(lumbago, neck pain) and a stiff muscle sensation(shoulder tension, t4ension
feeling
of lower limb). Among 22 patients, there were 14 lumbagos, tow cephalobrachial syndromes, one scapulohumeral periarthritis, and five combined patients were chosen and duration of symptom was 5 years (3months)15years) in average. Mulex tablet was
administered in a dose of 3 tablets (150mg) per day in 22 patients for 6 weeks prospectively. We analysed general improvement rating9GIR), general usefulness rating 9GUR), and overall safety rating. The general improvement rate was 78% and the
aggravation rate was 4%. The complication after, madication was infrequently gastrointestinal trouble. Incidence of side effect was 22%, but all these complications were insignificant. Hematology, blood chemistry, and urinalysis after medication
were
normal.
|